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Ovarian & Rare Cancer Laboratory

Centre Head
19 members

About the lab

I lead an ovarian cancer laboratory focused on developing targeted therapies for ovarian cancer and other rare cancers. Our aim is to change the current treatment paradigm of “one size fits all” for women with ovarian cancer. This involves the use of novel pre-clinical models of epithelial ovarian cancer, complementing my activities as a medical oncologist in rare gynaecological cancers and cancer genetics.

Our mission

We focus on designing novel treatments targeted to specific molecules that are altered in ovarian cancer and other rare cancer types, with an emphasis on unraveling causes of drug resistance.

Impact

My research has contributed to novel therapy in ovarian and rare cancers. From developing new therapies targeting gene or molecular defects in high grade serous ovarian cancer (HGSOC) (for example PARP inhibtors for treating ovarian cancer) to establishing The WEHI-Stafford Fox Rare Cancer Research Program which is aimed at developing new strategies for diagnosing and treating patients with rare cancers.

Lab research projects

Lab team

The Scott laboratory has a strong emphasis on research that has potential for clinical translation.

Our relatively large laboratory is made up of a combination of clinician scientists, postdoctoral fellows, students, research assistants and genetic counsellors. We have a strong collaborative ethic and while the lab works across cancer types, technical expertise and resources are shared between both groups.

There is a variety of expertise within the group including bioinformatics, genomics and cell biology. We develop and study pre-clinical models such as patient-derived xenografts, organoids and cell lines and perform functional genomic screens.

19 members
Imalki Kariyawasam
PhD Student
Elizabeth Kyran
Visiting PhD Student
Anthony Hadla
PhD Student
Asha Bound
Visiting PhD Student
Sally Beard
Research Assistant
Research Officer
Chloe Neagle
Research Assistant
Research Assistant
Research Assistant
Dr Ratana Lim
Laboratory Manager
Senior Research Officer
Clinical Research Fellow
Senior Research Officer
Silvia Stoev
Research Assistant
Amandine Carmagnac
Research Assistant
Dr Cassandra Vandenberg
Senior Research Officer
Senior Research Officer
Kathy Barber
Research Assistant
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