Ian Street-publications

Ian Street-publications

Researcher: 

Publications

  1. Brady, R. M.; Vom, A.; Roy, M. J.; Toovey, N.; Smith, B. J.; Moss, R. M.; Hatzis, E.; Huang, D. C. S.; Parisot, J. P.; Yang, H.; Street, I. P.; Colman, P. M.; Czabotar, P. E.; Baell, J. B.; Lessene, G. De-Novo Designed Library of Benzoylureas as Inhibitors of BCL-XL: Synthesis, Structural and Biochemical Characterization. J. Med. Chem. 2014, 57, 1323–1343. PMID:24456288
  2. Lackovic, K., Falk, H. Leuchowius, K. Lessene, G., Baell J. & Street I. A Perspective on 10-Years HTS Experience at the Walter and Eliza Hall Institute of Medical Research – Eighteen Million Assays and Counting.  Combinatorial Chemistry and High Throughput Screening. 2014, 17(3):241-252. PMID: 24409955
  3. Zhang, L.; Holmes, I. P.; Hochgräfe, F.; Walker, S. R.; Ali, N. A.; Humphrey, E. S.; Wu, J.; de Silva, M.; Kersten, W. J. A.; Connor, T.; Falk, H.; Lynda, A.; Street, I. P.; D., B. J.; Pilling, P.; Monahan, B. J.; Peat, T. S.; Daly, R. J. Characterization of the novel broad-spectrum kinase inhibitor CTx-0294885 as an affinity reagent for mass spectrometry-based kinome profiling. J. Proteome 2013, 12, 3104–3116. PMID: 23692254 
  4. Lessene, G.; Czabotar, P. E.; Sleebs, B. E.; Zobel, K.; Lowes, K. N.; Adams, J. M.; Baell, J. B.; Colman, P. M.; Deshayes, K.; Fairbrother, W. J.; Flygare, J. a; Gibbons, P.; Kersten, W. J. A; Kulasegaram, S.; Moss, R. M.; Parisot, J. P.; Smith, B. J.; Street, I. P.; Yang, H.; Huang, D. C. S.; Watson, K. G. Structure-guided design of a selective BCL-X(L) inhibitor. Nat. Chem. Biol. 2013, 9, 390–7. PMID:23603658.
  5. Li, R.; Doherty, J.; Antonipillai, J.; Chen, S.; Devlin, M.; Visser, K.; Baell, J.; Street, I.; Anderson, R. L.; Bernard, O. LIM kinase inhibition reduces breast cancer growth and invasiveness but systemic inhibition does not reduce metastasis in mice. Clin. Exp. Metastasis 2013, 30, 483–95. PMID: 23239465
  6. Willoughby, L. F.; Schlosser, T.; Manning, S. A.; Parisot, J. P.; Street, I. P.; Richardson, H. E.; Humbert, P. O.; Brumby, A. M. An in vivo large-scale chemical screening platform using Drosophila for anti-cancer drug discovery. Dis. Model. Mech. 2013, 6, 521–529. PMID: 22996645
  7. Sleebs, B.E., P.E. Czabotar, W.J. Fairbrother, W.D. Fairlie, J.A. Flygare, D.C.S. Huang, W.J.A. Kersten, M.F.T. Koehler, G. Lessene, K. Lowes, J.P. Parisot, B.J. Smith, M.L. Smith, A.J. Souers, I.P. Street, H. Yang, and J.B. Baell, Quinazoline Sulfonamides as Dual Binders of the Proteins B-Cell Lymphoma 2 and B-Cell Lymphoma Extra Long with Potent Proapoptotic Cell-Based Activity. Journal of Medicinal Chemistry, 2011. 54(6): p. 1914-1926. PMID: 21366295.
  8. Patterson, S., M.S. Alphey, D.C. Jones, E.J. Shanks, I.P. Street, J.A. Frearson, P.G. Wyatt, I.H. Gilbert, and A.H. Fairlamb, Dihydroquinazolines as a Novel Class of Trypanosoma brucei Trypanothione Reductase Inhibitors: Discovery, Synthesis and Characterization of their Binding Mode by Protein Crystallography. Journal of Medicinal Chemistry, 2011: 13; 54(19):6514-30. PMID: 21851087
  9. Sleebs, B.E., G. Nikolakopoulos, I.P. Street, H. Falk, and J.B. Baell, Identification of 5,6-substituted 4-aminothieno[2,3-d]pyrimidines as LIMK1 inhibitors. Bioorganic & Medicinal Chemistry Letters, 2011; 21(19):5992-4. PMID: 21852129
  10. Falk, H., T. Connor, H. Yang, K.J. Loft, R.N. Surjadi, J.D. Bentley, M.K. Hattarki, O. Dolezal, J.M. Murphy, B.J. Monahan, T.S. Peat, T. Thomas, J.B. Baell, J.P. Parisot, and I.P. Street, An Efficient High-Throughput Screening Method for MYST Family Acetyltransferases, a New Class of Epigenetic Drug Targets. Journal of Biomolecular Screening, 2011; 16(10):1196-205. PMID: PMID:22086725