Marnie Blewitt-Publications

Marnie Blewitt-Publications

Selected publications

  1. Chen K, Czabotar P, Blewitt ME* and Murphy JM* (2016) The hinge domain of the epigenetic repressor, Smchd1, adopts an unconventional homodimeric configuration. Biochem J. 2016 Mar 15;473(6):733-42 * Contributed equally. PMID: 6733688  
  2. Keniry AJ*, Gearing LJ*, Jansz N, Liu J, Holik A, Hickey P, Kinkel SA, Moore DL, Breslin K, Chen K, Liu R, Phillips C, Pakusch M, Biben C, Sheridan J, Kile BT, Carmichael C, Ritchie ME, Hilton DJ and Blewitt ME. (2016) Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in epigenetic silencing. Epigenetics Chromatin, in press, accepted March 31. IF 5.33. * Equal contribution
  3. Chen K, Dobson RC, Lucet IS, Young SN, Pearce FG, Blewitt ME* and Murphy JM* (2016) The epigenetic regulator Smchd1 contains a functional GHKL-type ATPase domain. Biochem J. in press, accepted April 8. * Contributed equally  PMID: 27059856
  4. Kinkel SA, Galeev R, Flensburg C, Keniry A, Breslin K, Gilan O, Lee S, Liu J, Chen K, Gearing LJ, Moore DL, Alexander WS, Dawson M, Majewski IJ, Oshlack A, Larsson J, Blewitt ME. Jarid2 regulates hematopoietic stem cell function by acting with polycomb repressive complex 2. Blood. 2015 Mar 19. PMID: 25645357
  5. Chen K, Hu J, Moore DL, Liu R, Kessans SA, Breslin K, Lucet IS, Keniry A, Leong HS, Parish CL, Hilton DJ, Lemmers RJ, van der Maarel SM, Czabotar PE, Dobson RC, Ritchie ME, Kay GF, Murphy JM, Blewitt ME. Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation. Proc Natl Acad Sci U S A. 2015 Jul 7. PMID: 26091879
  6. Dai Z, Sheridan JM, Gearing LJ, Moore DL, Su S, Dickins RA, Blewitt ME, Ritchie ME. shRNA-seq data analysis with edgeR. F1000Res. 2014;3:95. PMID: 24860646.
  7. Blewitt M, Whitelaw E. The use of mouse models to study epigenetics. Cold Spring Harb Perspect Biol. 2013 Nov;5(11):a017939. PMID: 24186070.
  8. Mould AW, Pang Z, Pakusch M, Tonks ID, Stark M, Carrie D, Mukhopadhyay P, Seidel A, Ellis JJ, Deakin J, Wakefield MJ, Krause L, Blewitt ME, Kay GF. Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation. Epigenetics Chromatin. 2013;6(1):19. PMID: 23819640.
  9. Leong HS, Chen K, Hu Y, Lee S, Corbin J, Pakusch M, Murphy JM, Majewski IJ, Smyth GK, Alexander WS, Hilton DJ, Blewitt ME. Epigenetic regulator Smchd1 functions as a tumor suppressor. Cancer Res. 2013 Mar 1;73(5):1591-9. PMID: 23269277.
  10. Majewski IJ, Ritchie ME, Phipson B, Corbin J, Pakusch M, Ebert A, Busslinger M, Koseki H, Hu Y, Smyth GK, Alexander WS, Hilton DJ, Blewitt ME. Opposing roles of polycomb repressive complexes in hematopoietic stem and progenitor cells. Blood. 2010 Aug 5;116(5):731-9. PMID: 20445021.
  11. Blewitt ME, Gendrel AV, Pang Z, Sparrow DB, Whitelaw N, Craig JM, Apedaile A, Hilton DJ, Dunwoodie SL, Brockdorff N, Kay GF, Whitelaw E. SmcHD1, containing a structural-maintenance-of-chromosomes hinge domain, has a critical role in X inactivation. Nat Genet. 2008 May;40(5):663-9. PMID: 18425126.