N Benetti, Q Gouil, A Tapia Del Fierro, T Beck, K Breslin, A Keniry, E McGlinn*, ME BLEWITT*. Maternal SMCHD1 regulates Hox gene expression and patterning in the mouse embryo. NATURE COMMUNICATIONS. 2022 Jul 25;13(1):4295.
A Keniry*, N Jansz, PF Hickey, K Breslin, M Iminitoff, T Beck, QA Gouil, ME Ritchie, ME BLEWITT*. A method for stabilising the XX karyotype in female mESC cultures. DEVELOPMENT 2022 Nov 15;149(22)
A Keniry*, N Jansz, LJ Gearing, I Wanigasuriya, J Chen, CM Nefzger, PF Hickey, Q Gouil, J Liu, KA Breslin, M Iminitoff, T Beck, A Tapia del Fierro, L Whitehead, A Jarratt, SA Kinkel, PC Taberlay, T Willson, M Pakusch, ME Ritchie, DJ Hilton, JM Polo, ME BLEWITT* Xmas mESC: A female embryonic stem cell system that reveals the BAF complex as a key regulator of establishment of X chromosome inactivation. NATURE COMMUNICATIONS 2022 Mar 29;13(1):1658
I Wanigasuriya*, QA Gouil*, SA Kinkel, A Tapia Del Fierro, T Beck, EA Roper, K Breslin, J Stringer, K Hutt, HJ Lee, A Keniry, ME Ritchie, ME BLEWITT. Smchd1 is a maternal effect gene required for genomic imprinting. eLIFE 2020 Nov 13;9:e55529
N Jansz, T Nesterova, A Keniry, M Iminitoff, PF Hickey, G Pintacuda, O Masui, S Kolbeke, N Geoghegan, KA Breslin, TA Willson, K Rogers, GF Kay, AH Fox, H Koseki, N Brockdorff, JM Murphy, ME BLEWITT. Smchd1 targeting to the inactive X is dependent on the Xist-HnrnpK-PRC1 pathway. CELL REPORTS 2018 Nov 1;25(7):1912-192
N Jansz, A Keniry, M Trussart, H. Bildsoe, T. Beck, ID Tonks, AW Mould, P Hickey, K Breslin, M Iminitoff, ME Ritchie, E McGlinn, GF Kay, JM Murphy and ME Blewitt Smchd1 regulates long-range chromatin interactions on the inactive X chromosome and at Hox clusters. NAT STRUCT MOL BIOL 2018 25, 766-777
CT Gordon^, S Xue^, G Yigit^, H Filali^, K Chen^, N Rosin, KI Yoshiura, M Oufadem, TJ Beck, R McGowan, AC Magee, J Altmüller, C Dion, H Thiele, AD Gurzau, … JM Murphy, C Chatdokmaiprai, AM Hillmer, D Wattanasirichaigoon, S Lyonnet, F Magdinier, A Javed*, ME BLEWITT*, J Amiel*, B Wollnik*, B Reversade* De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development. NATURE GENETICS 2017 Feb;49(2):249-255
K Chen, J Hu, DL Moore, R Liu, SA Kessans, K Breslin, IS Lucet, A Keniry, HS Leong, CL Parish, DJ Hilton, RJ Lemmers, SM van der Maarel, PE Czabotar, RC Dobson, ME Ritchie, GF Kay*, JM Murphy*, ME BLEWITT* Genome-wide binding and mechanistic analyses of Smchd1-mediated epigenetic regulation. PROC NATL ACAD SCI USA 2015 Jul 7;112(27):55-44