Peter Colman-Publications

Peter Colman-Publications

Publications

  1. Colman PM. Crystallography and New Medicines: Examples from Influenza and Cell Death. Australian Journal of Chemistry. 2014 Aug online
  2. Campbell S, Thibault J, Mehta N, Colman PM, Barry M, Kvansakul M. Structural Insight into BH3 Domain Binding of Vaccinia Virus Antiapoptotic F1L. Journal of Virology. 2014 Aug;88(15):8667-77. PMID: WOS:000338924400040.
  3. Brady RM, Vom A, Roy MJ, Toovey N, Smith BJ, Moss RM, Hatzis E, Huang DCS, Parisot JP, Yang H, Street IP, Colman PM, Czabotar PE, Baell JB, Lessene G. De-Novo Designed Library of Benzoylureas as Inhibitors of BCL-X-L: Synthesis, Structural and Biochemical Characterization. Journal of Medicinal Chemistry. 2014 Feb 27;57(4):1323-43. PMID: WOS:000332187700014.
  4. Koehler MFT, Bergeron P, Choo EF, Lau K, Ndubaku C, Dudley D, Gibbons P, Sleebs BE, Rye CS, Nikolakopoulos G, Bui C, Kulasegaram S, Kersten WJA, Smith BJ, Czabotar PE, Colman PM, Huang DCS, Baell JB, Watson KG, Hasvold L, Tao ZF, Wang L, Souers AJ, Elmore SW, Flygare JA, Fairbrother WJ, Lessene G. Structure-Guided Rescaffolding of Selective Antagonists of BCL-X-L. Acs Medicinal Chemistry Letters. 2014 Jun;5(6):662-7. PMID: WOS:000337497200012.
  5. Yao SG, Westphal D, Babon JJ, Thompson GV, Robin AY, Adams JM, Colman PM, Czabotar PE. NMR studies of interactions between Bax and BH3 domain-containing peptides in the absence and presence of CHAPS. Archives of Biochemistry and Biophysics. 2014 Mar 1;545:33-43. PMID: WOS:000332751700004.
  6. Sleebs BE, Kersten WJA, Kulasegaram S, Nikolakopoulos G, Hatzis E, Moss RM, Parisot JP, Yang H, Czabotar PE, Fairlie WD, Lee EF, Adams JM, Chen L, van Delft MF, Lowes KN, Wei A, Huang DCS, Colman PM, Street IP, Baell JB, Watson K, Lessene G. Discovery of Potent and Selective Benzothiazole Hydrazone Inhibitors of Bcl-X-L. Journal of Medicinal Chemistry. 2013 Jul 11;56(13):5514-40. PMID: WOS:000321884200023.
  7. Lessene G, Czabotar PE, Sleebs BE, Zobel K, Lowes KN, Adams JM, Baell JB, Colman PM, Deshayes K, Fairbrother WJ, Flygare JA, Gibbons P, Kersten WJA, Kulasegaram S, Moss RM, Parisot JP, Smith BJ, Street IP, Yang H, Huang DCS, Watson KG. Structure-guided design of a selective BCL-X-L inhibitor. Nature Chemical Biology. 2013 Jun;9(6):390-+. PMID: WOS:000319328200011.
  8. Czabotar PE, Westphal D, Dewson G, Ma S, Hockings C, Fairlie WD, Lee EF, Yao SG, Robin AY, Smith BJ, Huang DCS, Kluck RM, Adams JM, Colman PM. Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis. Cell. 2013 Jan 31;152(3):519-31. PMID: WOS:000314362800021.
  9. Colman PM. Early days in drug discovery by crystallography - personal recollections. Acta Crystallographica Section A. 2013 Jan;69:60-2. PMID: WOS:000312560800011.
  10. Boersma M, Haase H, Peterson-Kaufman K, Lee E, Clarke O; Colman P, Smith B, Horne W, Fairlie W, Gellman S (2012) Evaluation of Diverse α/β Backbone Patterns for Functional α-Helix Mimicry: Analogues of the Bim BH3 Domain. J Am Chem Soc 134:315-323. PMID:22040025