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- A new regulator of stemness to create dendritic cell factories for immunotherapy
- Advanced methods for genomic rearrangement detection
- Control of cytokine signaling by SOCS1
- Defining the protein modifications associated with respiratory disease
- Delineating the pathways driving cancer development and therapy resistance
- Developing a new drug that targets plasmacytoid dendritic cells for the treatment of lupus
- Development and mechanism of action of novel antimalarials
- Development of a novel particle-based malaria vaccine
- Discovering novel therapies for major human pathogens
- Dissecting host cell invasion by the diarrhoeal pathogen Cryptosporidium
- Epigenetic biomarkers of tuberculosis infection
- Essential role of glycobiology in malaria parasites
- Evolution of haematopoiesis in vertebrates
- Human lung protective immunity to tuberculosis
- Identifying novel treatment options for ovarian carcinosarcoma
- Interaction with Toxoplasma parasites and the brain
- Interactions between tumour cells and their microenvironment in non-small cell lung cancer
- Investigating the role of mutant p53 in cancer
- Microbiome strain-level analysis using long read sequencing
- Minimising rheumatic adverse events of checkpoint inhibitor cancer therapy
- Modelling spatial and demographic heterogeneity of malaria transmission risk
- Naturally acquired immune response to malaria parasites
- Predicting the effect of non-coding structural variants in cancer
- Structural basis of catenin-independent Wnt signalling
- Structure and biology of proteins essential for Toxoplasma parasite invasion
- T lymphocytes: how memories are made
- TICKER: A cell history recorder for longitudinal patient monitoring
- Targeting host pathways to develop new broad-spectrum antiviral drugs
- Targeting post-translational modifications to disrupting the function of secreted proteins
- Targeting the epigenome to rewire pro-allergic T cells
- Targeting the immune microenvironment to treat KRAS-mutant adenocarcinoma
- The E3 ubiquitin ligase Parkin and mitophagy in Parkinson’s disease
- The molecular controls on dendritic cell development
- Understanding malaria infection dynamics
- Understanding the genetics of neutrophil maturation
- Understanding the neuroimmune regulation of innate immunity
- Understanding the proteins that regulate programmed cell death at the molecular level
- Using cutting-edge single cell tools to understand the origins of cancer
- When healthy cells turn bad: how immune responses can transition to lymphoma
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Professor Suzanne Cory

Director, 1996 – 2009
Professor Suzanne Cory is one of Australia’s most distinguished molecular biologists. As director of the Institute she energetically promoted science policy and research at both the national and international level.
Leadership
Under Professor Cory’s leadership, the Institute focused on four big global medical challenges: cancer, immunity, autoimmunity and infectious diseases.
New disciplines were embraced, including bioinformatics, structural biology, medicinal chemistry, genomics and large-scale targeted mutagenesis, enabling a truly multidisciplinary approach to tackling human disease.
Professor Cory, Dr Alan Harris, Professor Andreas Strasser
and Professor David Vaux
The Institute became a world leader in apoptosis research, following the discovery in 1988 by Professor David Vaux with Professor Cory and Professor Jerry Adams that the gene causing human follicular lymphoma acts by blocking the central cell death pathway.
Other key achievements of the period included:
- The identification, for the first time, of the breast stem cell
- The discovery of how immune responses are regulated by apoptosis, the natural program of cell death
- Pioneering a systems biology approach to understanding the immune system
- Development of vaccines for type 1 diabetes and coeliac disease
- A promising new treatment for rheumatoid arthritis
- Significant advances in malaria research including development of vaccine candidates
- Enormous strides forward in understanding the regulation of blood cell production
- Building development
Like her predecessor, Sir Gustav Nossal, Professor Cory was faced with an Institute rapidly outgrowing its premises.
She was instrumental in securing funding and key stakeholder support for the $185 million redevelopment of the Parkville building. Completed in 2012, the redeveloped building doubled the Institute’s research capacity and provided world-class laboratories to support and inspire our staff.
Clinical and commercial links
Rapidly translating new discoveries into improved treatments and preventative strategies for patients continued to be a core focus under Cory.
at the opening of the new Biotechnology Centre in 2002
The new Parkville building was designed to include a dedicated Clinical Translation Centre, strengthening links with clinicians in The Royal Melbourne Hospital and elsewhere.
The Institute also established the Biotechnology Centre within the research and development park at La Trobe University. The Bundoora campus provides facilities for drug discovery and development, to enhance our capacity for moving basic research discoveries further along the R&D pipeline.
Looking towards the next generation
Lynne Kosky at the Gene Technology Access Centre
To generate enthusiasm for science among school students, and to foster excellence in science education in schools, Cory initiated a partnership to establish the Gene Technology Access Centre (GTAC). GTAC provides innovative laboratory programs in cell and molecular biology for more than 6000 school students and 800 science teachers every year.
After her term as director finished, Professor Cory became President of the Australian Academy of Science. She continues her research at the Institute as an honorary distinguished research fellow in the Blood Cells and Blood Cancer division.