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- A new regulator of 'stemness' to create dendritic cell factories for immunotherapy
- Advanced imaging interrogation of pathogen induced NETosis
- Cancer driver deserts
- Cryo-electron microscopy of Wnt signalling complexes
- Deciphering the heterogeneity of breast cancer at the epigenetic and genetic levels
- Developing drugs to block malaria transmission
- Developing new computational tools for CRISPR genomics to advance cancer research
- Developing novel antibody-based methods for regulating apoptotic cell death
- Discovering novel paradigms to cure viral and bacterial infections
- Discovery and targeting of novel regulators of transcription
- Dissecting host cell invasion by the diarrhoeal pathogen Cryptosporidium
- Do membrane forces govern assembly of the deadly apoptotic pore?
- Doublecortin-like kinases, drug targets in cancer and neurological disorders
- E3 ubiquitin ligases in neurodegeneration, autoinflammation and cancer
- Engineering improved CAR-T cell therapies
- Epigenetic biomarkers of tuberculosis infection
- Exploiting cell death pathways in regulatory T cells for cancer immunotherapy
- Finding treatments for chromatin disorders of intellectual disability
- Functional epigenomics in human B cells
- Genomic rearrangement detection with third generation sequencing technology
- How does DNA damage shape disease susceptibility over a lifetime?
- How does DNA hypermutation shape the development of solid tumours?
- How platelets prevent neonatal stroke
- Human lung protective immunity to tuberculosis
- Interaction with Toxoplasma parasites and the brain
- Interactions between tumour cells and their microenvironment in non-small cell lung cancer
- Investigating the role of dysregulated Tom40 in neurodegeneration
- Investigating the role of mutant p53 in cancer
- Lupus: proteasome inhibitors and inflammation
- Machine learning methods for somatic genome rearrangement detection
- Malaria: going bananas for sex
- Measurements of malaria parasite and erythrocyte membrane interactions using cutting-edge microscopy
- Measuring susceptibility of cancer cells to BH3-mimetics
- Minimising rheumatic adverse events of checkpoint inhibitor cancer therapy
- Mutational signatures of structural variation
- Naturally acquired immune response to malaria parasites
- Predicting the effect of non-coding structural variants in cancer
- Revealing the epigenetic origins of immune disease
- Reversing antimalarial resistance in human malaria parasites
- Structural and functional analysis of DNA repair complexes
- Targeting human infective coronaviruses using alpaca antibodies
- Towards targeting altered glial biology in high-grade brain cancers
- Uncovering the real impact of persistent malaria infections
- Understanding Plasmodium falciparum invasion of red blood cells
- Understanding how malaria parasites sabotage acquisition of immunity
- Understanding malaria infection dynamics
- Understanding the mechanism of type I cytokine receptor activation
- Unveiling the heterogeneity of small cell lung cancer
- Using alpaca antibodies to understand malaria invasion and transmission
- Using combination immunotherapy to tackle heterogeneous brain tumours
- Using intravital microscopy for immunotherapy against brain tumours
- Using nanobodies to cross the blood brain barrier for drug delivery
- Using structural biology to understand programmed cell death
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Annual reports
If you would like a hard copy or earlier annual reports, including highlights and financial statements, email communityrelations@wehi.edu.au or phone +61 3 9345 2555.
2021 Annual Report
The 2021 Annual Report showcases an exciting year of discoveries, partnerships and organisational activity at WEHI. A few highlights include:
- the Brain Cancer Centre, founded by Carrie’s Beanies 4 Brain Cancer and established in partnership with WEHI
- the Centre for Biologic Therapies, launched by WEHI in partnership with our long-term collaborator CSL
- WEHI’s multidisciplinary response to find much-needed treatments, rapid diagnostic tools and optimal vaccine strategies for COVID-19
Our 2021 Annual Report again includes augmented reality experiences. Download the WEHI AR app to your smartphone and use it to scan the augmented reality content on the cover and elsewhere throughout the report.
Visit the WEHI AR page for further information.
2020 Annual Report
WEHI launched its new brand in 2020, heralding a bright new era for our institute. The 2020 Annual Report describes this journey as well as research highlights, including:
- WEHI's response to the COVID-19 pandemic, including the launch of a new multidisciplinary coronavirus research program.
- Progress towards better treatments for several types of cancer, as well as degenerative conditions and iron deficiency.
- The discovery of the cellular and molecular origins of different blood cell types.
Our 2020 Annual Report includes augmented reality experiences. Download the WEHI AR app to your smartphone and use it to scan the augmented reality content on the cover and elsewhere throughout the report.
Visit the WEHI AR page for further information.
2019 Annual Report
Highlights from the Institute in 2019 include:
- Implementing the first year of our Strategic Plan 2019-2023, supporting our commitment to improving the lives of those suffering from disease
- Establishing the National Drug Discovery Centre to bring medicines to patients sooner
- Anti-cancer treatment venetoclax listed on the Australian PBS
2018 Annual Report
This annual report highlights how our decade-long commitment to recruiting a new generation of scientific leaders has paid dividends.
Our scientific achievements of 2018 include:
- landmark discoveries about the molecules driving lung cancer
- studies that improve the management of coeliac disease
- discoveries providing new insights into cell biology, enabled by our Centre for Dynamic Imaging
2017 Annual Report
In 2017 our scientists led many advances in both fundamental and translational research. These include:
- progressing clinical trials in breast cancer
- explaining in more detail how the body maintains balance in the immune system for good health
- applying bioinformatics and imaging techniques to unravel the biology of a neglected parasitic disease
2016 Annual Report
The 2016 Annual Report showcases an exciting year of scientific and organisational activity at the Institute.
Several key research advances shed light on fundamental biological processes, moving us closer to better health outcomes for patients. Among these are:
- a potential new approach to breast cancer in women who carry the BRCA1 gene
- using the genome sequence of the scabies and malaria parasites to identify potential new treatment approaches
- study of cone snail venom to inform more efficient therapies for diabetes
2015 Annual Report
"If one message came from our researchers and our supporters in 2015, it was that there is great optimism and hope for all that the Institute can achieve in its second century," Institute director Professor Doug Hilton
This past year has seen advances in understanding how malaria persists in populations, the development of potential new treatments for cancers, and new insights into immune disorders, including immunodeficiencies, allergies and coeliac disease.
2014 Annual Report
This report covers only six months due to the change in financial year, to better align the Institute with the government grant cycle.
This year, in consultation with staff, students, supporters and collaborators, we have been developing a new five-year strategic plan that will follow on from our current plan, guiding our operations from 2015 to 2020.
Our researchers have made many exciting research breakthroughs this year, and have been duly rewarded with notable prizes and competitive grants.
View the Financial Statements 1 July - 31 December 2014.
2013-2014 Annual Report
The Institute's 2013-2014 Annual Report includes highlights from the previous 12 months of research, translation, education, engagement and sustainability activities at the Institute.
- Finding the cause of inflammatory disease
- Prime Minister's Prize for Science to Professor Terry Speed
- Trial results bringing high hopes for advanced leukaemia
- Viruses light White Night festival
- Acknowledging and thanking our supporters
2012-2013 Annual Report
The Institute is home to almost 750 researchers who are working to understand, prevent and treat diseases including cancer, immune disorders and infectious diseases.
Making major discoveries requires teams of researchers and clinicians who are willing to work with each other over many years while supported by stable funding. We would like to take this opportunity to thank you all and to encourage you to read this report and take pride in the work that you have allowed to happen.
Archive
Download a copy of an annual report; all files are in PDF format.