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- 3D and 4D imaging of thymic T cell differentiation
- Activating https://www.wehi.edu.au/node/add/individual-student-research-page#Parkin to treat Parkinson’s disease
- Activation, regulation, and biological roles of E3 ubiquitin ligases
- Bioinformatics methods for detecting and making sense of somatic genomic rearrangements
- Characterising regulatory T cells in coeliac disease
- Computational melanoma genomics
- Deep profiling of blood cancers during targeted therapy
- Defining the role of necroptosis in platelet production and function
- Determining the migration signals leading to protective immune responses
- Developing mucolytics to treat chronic respiratory diseases
- Developing new tools to visualise necroptotic cell death
- Development of live-cell, automated microscopy techniques for studying malaria
- Development of tools to inform malaria vaccine design
- Discovering new genetic causes of primary antibody deficiencies
- Discovery of novel drug combinations for the treatment of bowel cancer
- Dissecting the induction and integration of T cell migration cues
- Drug targets and compounds that block growth of malaria parasites
- Effects of nutrition on immunity and infection in Asia and Africa
- Eosinophil and neutrophil heterogeneity
- Eosinophil maturation
- Epigenetic regulation of systemic iron homeostasis
- Functional differences between young and old platelets
- Generation of cytokine antagonists
- Genetic dissection of mechanisms of Plasmodium invasion
- Genomic characterisation of epigenetic regulators involved in X inactivation
- High resolution 3-dimensional imaging to characterise metastatic cancers
- High-resolution imaging of host cell invasion by the malaria parasite
- Home renovations: understanding how Toxoplasma redecorates its host cell
- How the epigenetic regulator SMCHD1 works and how to target it to treat disease
- Human monoclonal antibodies against malaria infection
- Identification of malaria parasite entry receptors
- Identification of new therapeutic opportunities for pancreatic cancer
- Identifying disease-causing haplotypes with hidden Markov models
- Interleukin-11 in gastrointestinal bacterial infections
- Investigating mechanisms of cell death and survival using zebrafish
- Investigating new paths to selective modulation of potassium channels
- Let me in! How Toxoplasma invades human cells
- Long-read sequencing for transcriptome and epigenome analysis
- Macro-evolution in cancer
- Mapping DNA repair networks in cancer
- Mapping how multiple malaria episodes are related
- Modelling gene regulatory systems
- Modulation of immune responses by immunosuppressive chemokines
- Molecular basis for inherited Parkinson’s disease mechanism of PINK1
- Mucus at the molecular level
- Novel cell death and inflammatory modulators in lupus
- Plasmodium vivax host-parasite interactions: impact on immunity
- Predicting drug response in cancer
- Programming T cells to defend against infections
- Reconstructing the immune response: from molecules to cells to systems
- Regulation of cytokine signalling
- Screening for regulators of jumping genes
- Target identification of potent antimalarial agents
- Targeting the immune system in cancer
- The role of interleukin-11 in acute myeloid leukaemia
- Transmembrane control of type I cytokine receptor activation
- Uncovering the roles of long non-coding RNAs in human bowel cancer
- Understanding retinal eye diseases with retinal transcriptomic data analysis
- Understanding the role of stromal cells in pancreatic cancer growth
- Unravelling the tumour suppressor network in models of lung cancer
- Utilising pre-clinical models to discover novel therapies for tuberculosis
- Zombieland: evolution of a dead enzyme that kills cells by necroptosis
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Annual reports
If you would like a hard copy or earlier annual reports, including highlights and financial statements, email information@wehi.edu.au or phone +61 3 9345 2555.
2017 Annual Report
In 2017 our scientists led many advances in both fundamental and translational research. These include:
- progressing clinical trials in breast cancer
- explaining in more detail how the body maintains balance in the immune system for good health
- applying bioinformatics and imaging techniques to unravel the biology of a neglected parasitic disease
2016 Annual Report
The 2016 Annual Report showcases an exciting year of scientific and organisational activity at the Institute.
Several key research advances shed light on fundamental biological processes, moving us closer to better health outcomes for patients. Among these are:
- a potential new approach to breast cancer in women who carry the BRCA1 gene
- using the genome sequence of the scabies and malaria parasites to identify potential new treatment approaches
- study of cone snail venom to inform more efficient therapies for diabetes
2015 Annual Report
"If one message came from our researchers and our supporters in 2015, it was that there is great optimism and hope for all that the Institute can achieve in its second century," Institute director Professor Doug Hilton
This past year has seen advances in understanding how malaria persists in populations, the development of potential new treatments for cancers, and new insights into immune disorders, including immunodeficiencies, allergies and coeliac disease.
2014 Annual Report
This report covers only six months due to the change in financial year, to better align the Institute with the government grant cycle.
This year, in consultation with staff, students, supporters and collaborators, we have been developing a new five-year strategic plan that will follow on from our current plan, guiding our operations from 2015 to 2020.
Our researchers have made many exciting research breakthroughs this year, and have been duly rewarded with notable prizes and competitive grants.
View the Financial Statements 1 July - 31 December 2014.
2013-2014 Annual Report
The Institute's 2013-2014 Annual Report includes highlights from the previous 12 months of research, translation, education, engagement and sustainability activities at the Institute.
- Finding the cause of inflammatory disease
- Prime Minister's Prize for Science to Professor Terry Speed
- Trial results bringing high hopes for advanced leukaemia
- Viruses light White Night festival
- Acknowledging and thanking our supporters
2012-2013 Annual Report
The Institute is home to almost 750 researchers who are working to understand, prevent and treat diseases including cancer, immune disorders and infectious diseases.
Making major discoveries requires teams of researchers and clinicians who are willing to work with each other over many years while supported by stable funding. We would like to take this opportunity to thank you all and to encourage you to read this report and take pride in the work that you have allowed to happen.
Archive
Download a copy of an annual report; all files are in PDF format.