Associate Professor Sheena D’Arcy - University of Texas at Dallas

Associate Professor Sheena D’Arcy - University of Texas at Dallas

Bio21 Auditorium
Start Time: 
Wed, 01/02/2023 - 2:00pm
End Time: 
Wed, 01/02/2023 - 3:00pm

WEHI Special Seminar hosted by Dr Laura Dagley (WEHI) and Dr Rob Ninnis (Trajan)

Associate Professor Sheena D’Arcy

Chemistry and Biochemistry, The University of Texas at Dallas

Hydrogen-Deuterium Exchange: Beyond the Integrated Structural Approach 


Bio21 Auditorium

Join via ZOOM

Webinar ID: 846 5552 0153

Passcode: 038826

Including Q&A session


Professor Sheena D'Arcy received her undergraduate advanced science degree with honours from the University of Sydney. Her love of structural biology then took her to the laboratory of Sir Professor Tom Blundell at the University of Cambridge where she was fortunate enough to learn X-ray crystallography. A passion for science and the outdoors then took her to the laboratory of Howard Hughes Investigator Karolin Luger in Colorado, where she studied histone chaperones and chromatin. It was during these postdoctoral training years that Sheena was first exposed to hydrogen-deuterium exchange coupled to mass spectrometry. 

In 2015 Sheena established her own research laboratory in the Department of Chemistry and Biochemistry at the University of Texas at Dallas. Her team investigates the regulation of local chromatin structure and tries to push the envelope in expanding the application of hydrogen-deuterium exchange. Her group is currently composed of 10 graduate students and 2 undergraduates and is funded by the National Institutes of Health. Sheena is the faculty advisor for the American Society of Biochemistry and Molecular Biology Chapter and serves as a board member on the International Society of Hydrogen-Deuterium Exchange and the University of Texas System Proteomics Network. She is a mother of three and is eagerly awaiting a time when she can bring them to see their grandparents in Australia. Today Sheena is going to share several stories involving HDX: ranging from drug-binding to epitope-mapping as well as novel RNA-protein complex analysis of the RNA helicase Mtr4, both alone and in the TRAMP complex.


Sheena is available for one-on-one meetings, contact Laura Dagley by 27 February.


All welcome!