Nick Confuorto PhD - Nanostring Technologies

Nick Confuorto PhD - Nanostring Technologies

Location: 
Seminar Room 1
Start Time: 
Wed, 16/10/2019 - 3:00pm
End Time: 
Wed, 16/10/2019 - 4:00pm

​Morphology-driven high-plex spatial analysis of tissue microenvironments

​Technical seminar hosted by Dr Daniela Zalchenstein

Spatial characterization of the immune contexture in the tumor microenvironment (TME) is essential for understanding the relationship between immune and tumor cells. However, it has proven difficult to perform such studies in a highly multiplexed manner using limited samples. To address this unmet need, we have developed an imaging and tissue-sampling platform designed to simultaneously analyze up to hundreds of tumor and immune proteins in distinct locations on a single FFPE tissue section. Using this novel technology, called Digital Spatial Profiling (DSP), we demonstrate multiplexed protein analysis of defined regions of interest within a tumor enabling systematic interrogation of the immune status in the tumor microenvironment
 
Nick Confuorto is the Global Manager responsible for the technical and commercial strategy on the Nanostring Digital Spatial Profiling technology (DSP). His expertise in the single cell multi-omics field, has helped to identify new applications useful to pathologists, oncologists and neurologists.