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- A complete cure for HBV
- A stable efficacious Toxoplasma vaccine
- Activating SMCHD1 to treat FSHD
- Improving vision outcomes in retinal detachment
- Novel inhibitors for the treatment of lupus
- Novel malaria vaccine
- Novel mucolytics for the treatment of respiratory diseases
- Precision epigenetics silencing SMCHD1 to treat Prader Willi Syndrome
- Rethinking CD52 a therapy for autoimmune disease
- Targeting minor class splicing
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- Anne-Laure Puaux
- Associate Profesor Ian Majewski
- Associate Professor Aaron Jex
- Associate Professor Alyssa Barry
- Associate Professor Andrew Webb
- Associate Professor Chris Tonkin
- Associate Professor Daniel Gray
- Associate Professor Diana Hansen
- Associate Professor Edwin Hawkins
- Associate Professor Emma Josefsson
- Associate Professor Ethan Goddard-Borger
- Associate Professor Grant Dewson
- Associate Professor Isabelle Lucet
- Associate Professor James Murphy
- Associate Professor James Vince
- Associate Professor Jason Tye-Din
- Associate Professor Jeanne Tie
- Associate Professor Jeff Babon
- Associate Professor Joan Heath
- Associate Professor Justin Boddey
- Associate Professor Kate Sutherland
- Associate Professor Marco Herold Marco Herold
- Associate Professor Marie-Liesse Asselin-Labat
- Associate Professor Matthew Ritchie
- Associate Professor Melissa Davis
- Associate Professor Misty Jenkins
- Associate Professor Nawaf Yassi
- Associate Professor Oliver Sieber
- Associate Professor Peter Czabotar
- Associate Professor Rachel Wong
- Associate Professor Rhys Allan
- Associate Professor Rosie Watson
- Associate Professor Ruth Kluck
- Associate Professor Sandra Nicholson
- Associate Professor Sant-Rayn Pasricha
- Associate Professor Seth Masters
- Associate Professor Sumitra Ananda
- Associate Professor Tim Thomas
- Associate Professor Wai-Hong Tham
- Associate Professor Wei Shi
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- Mr Mark Eaton
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- Professor Alan Cowman
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- Diseases
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- Student research projects
- A new regulator of 'stemness' to create dendritic cell factories for immunotherapy
- Advanced imaging interrogation of pathogen induced NETosis
- Can the 3D genome predict type 1 diabetes onset?
- Cancer driver deserts
- Choosing antibody type: B cells as a model system for cellular calculation and signal induced fate control
- Cryo-electron microscopy of Wnt signalling complexes
- Deciphering the heterogeneity of breast cancer at the epigenetic and genetic levels
- Developing drugs to block malaria transmission
- Developing new computational tools for CRISPR genomics to advance cancer research
- Developing novel antibody-based methods for regulating apoptotic cell death
- Development of tau-specific therapeutic and diagnostic antibodies
- Discovering novel paradigms to cure viral and bacterial infections
- Discovery and targeting of novel regulators of transcription
- Dissecting host cell invasion by the diarrhoeal pathogen Cryptosporidium
- Do membrane forces govern assembly of the deadly apoptotic pore?
- Doublecortin-like kinases, drug targets in cancer and neurological disorders
- E3 ubiquitin ligases in neurodegeneration, autoinflammation and cancer
- Engineering improved CAR-T cell therapies
- Epigenetic biomarkers of tuberculosis infection
- Exploiting cell death pathways in regulatory T cells for cancer immunotherapy
- Finding treatments for chromatin disorders of intellectual disability
- Functional epigenomics in human B cells
- Genomic rearrangement detection with third generation sequencing technology
- How does DNA damage shape disease susceptibility over a lifetime?
- How does DNA hypermutation shape the development of solid tumours?
- How lymphocytes are stopped - a novel mechanism to prevent lymphoma
- How platelets prevent neonatal stroke
- Human lung protective immunity to tuberculosis
- Interaction with Toxoplasma parasites and the brain
- Interactions between tumour cells and their microenvironment in non-small cell lung cancer
- Investigating the role of dysregulated Tom40 in neurodegeneration
- Investigating the role of mutant p53 in cancer
- Leukaemia is caused by mutations in DNA. This project will explore how 3D DNA structure influences when and where these DNA mutations occur. There is an opportunity for a dedicated and enthusiastic student to join our team and reveal how 3D genome organis
- Lupus: proteasome inhibitors and inflammation
- Machine learning methods for somatic genome rearrangement detection
- Malaria: going bananas for sex
- Measurements of malaria parasite and erythrocyte membrane interactions using cutting-edge microscopy
- Measuring susceptibility of cancer cells to BH3-mimetics
- Minimising rheumatic adverse events of checkpoint inhibitor cancer therapy
- Mutational signatures of structural variation
- Naturally acquired immune response to malaria parasites
- Predicting the effect of non-coding structural variants in cancer
- Revealing the epigenetic origins of immune disease
- Reversing antimalarial resistance in human malaria parasites
- Structural and functional analysis of DNA repair complexes
- Targeting human infective coronaviruses using alpaca antibodies
- The cellular and molecular calculation of life and death in lymphocyte regulation
- Towards targeting altered glial biology in high-grade brain cancers
- Uncovering the real impact of persistent malaria infections
- Understanding Plasmodium falciparum invasion of red blood cells
- Understanding how malaria parasites sabotage acquisition of immunity
- Understanding malaria infection dynamics
- Understanding the mechanism of type I cytokine receptor activation
- Unveiling the heterogeneity of small cell lung cancer
- Using alpaca antibodies to understand malaria invasion and transmission
- Using combination immunotherapy to tackle heterogeneous brain tumours
- Using intravital microscopy for immunotherapy against brain tumours
- Using nanobodies to cross the blood brain barrier for drug delivery
- Using structural biology to understand programmed cell death
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Aaron Jex - Lab team
Researcher:
Lab team
Louise Baker, Centenary Fellow, BSc(Hons) Melbourne PhD Melbourne
Samantha Emery, Senior Postdoctoral Fellow, BSc(Hons) Macquarie PhD Macquarie
Nijoy John, Postdoctoral Fellow, BSc Bangalore MSc Bangalore MSc Adelaide PhD Melbourne
Balu Balan, PhD Student, BSc Amrita MSc Amrita
Alex Lam, PhD Student, BSc(Hons) Melbourne
Pradip Roy, PhD Student, BSc Shahjalal MSc Shahjalal
Qiao Su, PhD Student, BBsMn China Pharmaceutical University MSc Chongqing
Swapnil Tichkule, PhD Student, BTech Dehradun MTech Allahabad
Amrita Vijay, PhD Student, BSc Amrita MSc Amrita
Marlene Walter, Master of Research Student, BSc HNE Eberswalde
Arash Zamyadi, Research Manager, MSc Laval PhD Montreal
Brianna Flynn, Research Assistant, BSc(Hons) Melbourne
Leon Hartman, Research Assistant, BSc(Hons) Swinburne PhD Swinburne
James Merrett, Research Assistant, BSc(Biotech) Adelaide PhD Adelaide
Super Content:
On World Water Day, Melbourne Water and the Walter and Eliza Hall Institute announced a joint research fellowship designed to improve the identification and control of water-borne illness.
Dr Samantha Emery has won a two-year grant from The Jack Brockhoff Foundation to support her studies in the parasite, Giardia duodenalis.
The Institute’s annual Art of Science exhibition has opened, with stunning images and videos captured by our researchers who are tackling some of the biggest challenges facing global health.
