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- Domain-specific BET bromodomain inhibitors for cancer
- Targeting BFL-1 for the treatment of cancer
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- Soluble CD52 as a therapeutic for inflammatory disease
- TBK inhibitors to treat rheumatoid arthritis
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- Associate Professor Aaron Jex
- Associate Professor Alyssa Barry
- Associate Professor Anne Voss
- Associate Professor Chris Tonkin
- Associate Professor Daniel Gray
- Associate Professor Edwin Hawkins
- Associate Professor Grant Dewson
- Associate Professor James Murphy
- Associate Professor Jeff Babon
- Associate Professor Joan Heath
- Associate Professor Justin Boddey
- Associate Professor Marco Herold Marco Herold
- Associate Professor Marnie Blewitt
- Associate Professor Mike Lawrence
- Associate Professor Nicholas Huntington
- Associate Professor Oliver Sieber
- Associate Professor Sandra Nicholson
- Associate Professor Seth Masters
- Associate Professor Tim Thomas
- Associate Professor Wai-Hong Tham
- Associate Professor Wei Shi
- Catherine Parker
- Dr Andrew Webb
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- Dr Diana Hansen
- Dr Drew Berry
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- Dr Ethan Goddard-Borger
- Dr Gary Pitt
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- Dr Hélène Jousset Sabroux
- Dr Ian Majewski
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- Dr Jacqui Gulbis
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- Dr Joanna Groom
- Dr John Wentworth
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- Dr Kate Sutherland
- Dr Kelly Rogers
- Dr Ken Pang
- Dr Leanne Robinson
- Dr Leigh Coultas
- Dr Marie-Liesse Asselin-Labat
- Dr Mary Ann Anderson
- Dr Maryam Rashidi
- Dr Matthew Call
- Dr Matthew Ritchie
- Dr Melissa Call
- Dr Melissa Davis
- Dr Michael Low
- Dr Misty Jenkins
- Dr Peter Czabotar
- Dr Philippe Bouillet
- Dr Priscilla Auyeung
- Dr Rhys Allan
- Dr Ruth Kluck
- Dr Samar Ojaimi
- Dr Samir Taoudi
- Dr Sant-Rayn Pasricha
- Dr Shalin Naik
- Dr Simon Chatfield
- Dr Stephen Wilcox
- Dr Tracy Putoczki
- Guillaume Lessene
- Helene Martin
- Isabelle Lucet
- Keely Bumsted-O'Brien
- Mr Ian Coulson
- Mr Joel Chibert
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- Ms Carolyn MacDonald
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- Professor Alan Cowman
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- Professor Clare Scott
- Professor David Huang
- Professor David Vaux
- Professor Doug Hilton
- Professor Gabrielle Belz
- Professor Geoff Lindeman
- Professor Gordon Smyth
- Professor Ian Wicks
- Professor Ivo Mueller
- Professor Jane Visvader
- Professor Jerry Adams
- Professor John Silke
- Professor Ken Shortman
- Professor Leonard C Harrison
- Professor Li Wu
- Professor Lynn Corcoran
- Professor Marc Pellegrini
- Professor Melanie Bahlo
- Professor Nicos Nicola
- Professor Peter Colman
- Professor Peter Gibbs
- Professor Phil Hodgkin
- Professor Stephen Nutt
- Professor Suzanne Cory
- Professor Terry Speed
- Professor Tony Burgess
- Professor Tony Papenfuss
- Professor Warren Alexander
- Education
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- Student research projects
- Analysis and reporting of whole genome sequencing data from malaria parasites
- Analysis of long read data from the minION, with application to malaria
- Analysis of short tandem repeat markers from whole genome sequencing
- Antibody longevity following Plasmodium vivax infections
- Antigenic diversity of malaria parasites: towards more effective malaria vaccines
- Biogenesis of eosinophil granules
- Biological sequence analysis and genomic variant discovery
- Biology of the unique intra-mitochondrial bacterium Midichloria mitochondrii
- Characterising regulatory T cells in coeliac disease
- Chemical probing to identify effectors of necroptotic cell death
- Computational systems biology of Wnt/cell adhesion signalling in colon cancer
- Controlling apoptotic cell death in cancer
- Deciphering mechanisms of thrombocytopenia (low platelet count) in blood cancers
- Defining molecular signatures of drug resistance and sensitivity
- Designing immunotherapy for brain cancer
- Developing non-invasive methods to monitor kidney transplant rejection
- Discovery and analysis of autoimmune regulators
- Discovery of novel drug combinations for the treatment of bowel cancer
- Drug targets and compounds that block growth of malaria parasites
- Dying to survive: mechanistic insights into human bowel cancer development
- Dynamic discovery of innate immunity through imaging and genomics
- Dysregulation of TNF expression in inflammatory diseases
- Effects of nutrition on immunity and infection in Asia and Africa
- Elucidation of long range methylation structure using nanopore sequencing
- Eosinophil activation
- Eosinophil death
- Eosinophil heterogeneity
- Eosinophil maturation
- Epigenetic regulation of systemic iron homeostasis
- Epigenetic regulation of the immune system
- Explosive cell death and human disease
- Export of malaria virulence proteins during liver infection
- Function of proteins involved in invasion of erythrocytes by malaria parasites
- Functional genomics to improve therapeutic options for rare cancers
- Giardia duodenalis phosphoproteome and protein kinase network
- Harnessing the immune system to target small cell lung cancer
- Home renovations: understanding how Toxoplasma redecorates its host cell
- How do malaria parasites traverse human cells and invade hepatocytes?
- How does the malaria parasite prevent the host liver cell from dying?
- Human monoclonal antibodies against malaria infection
- IL5 signalling in asthma
- Identification of genes critical for the control of chronic infections
- Identification of malaria parasite entry receptors
- Identifying new cell death and inflammatory pathways
- Identifying proteome signatures of high grade glioma for precision medicine
- Insight into the cytotoxic T cell immune synapse
- Investigating apoptosis control in tumour blood vessels
- Investigating brain abnormalities with single cell ‘omics
- Investigating mechanisms of cell death and survival using zebrafish
- Investigating the mechanics of platelet formation
- Investigating the molecular regulation of neovascular eye disease
- Let me in! How Toxoplasma invades human cells
- Long-read sequencing for transcriptome and epigenome analysis
- Machine learning analysis of mutagenesis datasets
- Macro-evolution in cancer
- Mapping human gene mutations affecting anti-malarial drug efficacy
- Mechanism and modulation of K+ channels and membrane transporters
- Mechanisms of disease relapse in acute lymphoblastic leukaemia
- Microbiome analysis using long read nanopore sequencing
- Molecular mechanism underpinning dendritic cell ontogeny and functions
- Molecular mechanisms of innate immune signalling
- Next-generation mucolytics to treat lung diseases
- No sex please, we’re inhibited: searching for drugs to prevent malaria transmission
- Novel biomarkers and mechanisms of antimalarial drug resistance
- Novel real-time, quantitative imaging approaches for studying malaria
- Novel regulators of JAK-STAT signalling in development and disease
- Novel tool for malaria surveillance and intervention
- Optimising serological markers of recent exposure to Plasmodium vivax
- Quantitation of human T cell responses in primary immunodeficiency
- Reconciling intracellular imaging and metastatic behaviour in cancer cells
- Reconstructing the immune response: from molecules to cells to systems
- Role of protein glycosylation in malaria virulence
- Statistical bioinformatic analyses of RNA-seq and ChIP-seq data
- Strategies mammalian cells use to survive without growth factors
- Structural and biochemical studies on Notch signal transduction
- Structural and functional analysis of malaria invasion
- Structural biology and binding studies of BCL-2 family proteins
- Structural studies of invasion processes during malaria infection
- Structural studies of the Plasmodium and Toxoplasma tight-junction complex
- Target identification of potent antimalarial agents
- The role of glycosylation in malaria vaccine design
- Towards a molecular description of plasma cell diversity
- Tracking the spread of malaria in the Asia Pacific region
- Transmembrane control of type I cytokine receptor activation
- Uncovering the roles of long non-coding RNAs in human bowel cancer
- Understanding resistance to apoptotic cell death
- Understanding the common through study of the rare
- Understanding the development of humoral immunity to malaria
- Unravelling cellular circuitry with single cell RNA-seq and CRISPR
- Unravelling the molecular architecture of killer T cells in disease
- Why is interleukin-11 elevated in acute myeloid leukaemia?
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Title: T cell receptor structure and function
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2014 The Walter and Eliza Hall Insitute of Medical Research. ABN: 12 004 251 423