Andrew Lew-Publications

Andrew Lew-Publications

Selected publications

  1. ​Zhan Y, Zhang Y, Zhang S, Coughlan H, Baldoni PL, Jacquelot N, Cao WHJ, Preston S, Louis C, Rautela J, Pellegrini M, Wicks IP, Alexander WS, Harrison LC, Lew AM, Smyth GK, Nutt SL, Chopin M.  Differential requirement for the Polycomb repressor complex 2 in dendritic cell and tissue-resident myeloid cell homeostasis. Sci Immunol. 2021 Sep 17;6(63):eabf7268. doi: 10.1126/sciimmunol.abf7268. Epub 2021 Sep 17. PMID: 34533976
  2. Carrington EM, Louis C, Kratina T, Hancock M, Keenan CR, Iannarella N, Allan RS, Wardak AZ, Czabotar PE, Herold MJ, Schenk RL, White CA, D'Silva D, Yang Y, Wong W, Wong H, Bryant VL, Huntington ND, Rautela J, Sutherland RM, Zhan Y, Hansen J, Nhu D, Lessene G, Wicks IP, Lew AM. BCL-XL antagonism selectively reduces neutrophil life span within inflamed tissues without  causing neutropenia.  Blood Adv. 2021 Jun 8;5(11):2550-2562. doi: 10.1182/bloodadvances.2020004139. PMID: 34100903 Free PMC article.
  3.  Zhang S, Coughlan HD, Ashayeripanah M, Seizova S, Kueh AJ, Brown DV, Cao W, Jacquelot N, D'Amico A, Lew AM, Zhan Y, Tonkin CJ, Villadangos JA, Smyth GK, Chopin M, Nutt SL. Type 1 conventional dendritic cell fate and function are controlled by DC-SCRIPT. Sci Immunol. 2021 Apr 2;6(58):eabf4432. doi: 10.1126/sciimmunol.abf4432.PMID: 33811060
  4. Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, Xu Y, Wu Q, Guo X, Nie J, Lu B, Huang B, Xian H, Wang X, Wu Q, Zeng J, Chai C, Zhang M, Lin Y, Zhang L, Zhao S, Tong Y, Zeng L, Gu X, Chen  ZG, Yi S, Zhang T, Delfouneso D, Zhang Y, Nutt SL, Lew AM, Lu L, Bai F, Xia H, Wen Z, Zhang Y. Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia. Cell. 2020 Dec  23;183(7):1867-1883.e26. doi: 10.1016/j.cell.2020.10.048. Epub 2020 Nov 27.PMID: 33248023
  5.  Lai J, Mardiana S, House IG, Sek K, Henderson MA, Giuffrida L, Chen AXY, Todd KL, Petley EV, Chan JD, Carrington EM, Lew AM, Solomon BJ, Trapani JA, Kedzierska K, Evrard M, Vervoort SJ,  Waithman J, Darcy PK, Beavis PA.  Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity. Nat Immunol. 2020  Aug;21(8):914-926. doi: 10.1038/s41590-020-0676-7. Epub 2020 May 18.PMID: 32424363
  6. Zhan Y, Kong I, Chopin M, Macri C, Zhang JG, Xie J, Nutt SL, O'Keeffe M, Hawkins ED, Morand EF, Lew AM. Plasmacytoid dendritic cells from parent strains of the NZB/W F1 lupus mouse  contribute different characteristics to autoimmune propensity. Immunol Cell Biol. 2020 Mar;98(3):203-214. doi: 10.1111/imcb.12313. Epub 2020 Feb 5.PMID: 31916630
  7.  Huang B, Chen Z, Geng L, Wang J, Liang H, Cao Y, Chen H, Huang W, Su M, Wang H, Xu Y, Liu Y, Lu B, Xian H, Li H, Li H, Ren L, Xie J, Ye L, Wang H, Zhao J, Chen P, Zhang L, Zhao S, Zhang  T, Xu B, Che D, Si W, Gu X, Zeng L, Wang Y, Li D, Zhan Y, Delfouneso D, Lew AM, Cui J, Tang WH, Zhang Y, Gong S, Bai F, Yang M, Zhang Y. Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways.  Cell. 2019 Nov 14;179(5):1160-1176.e24. doi: 10.1016/j.cell.2019.10.027.PMID: 31730855
  8. Sun L, Rautela J, Delconte RB, Souza-Fonseca-Guimaraes F, Carrington EM, Schenk RL, Herold MJ, Huntington ND, Lew AM, Xu Y, Zhan YGM-CSF Quantity Has a Selective Effect on Granulocytic vs. Monocytic Myeloid Development and Function. Front Immunol. 2018 Aug 28;9:1922. doi: 10.3389/fimmu.2018.01922. eCollection 2018. PMID: 30210491 Free PMC article.
  9. Sutherland RM, Londrigan SL, Brady JL, Carrington EM, Marchingo JM, Heinzel S, Hodgkin PD, Graham KL, Kay TW, Zhan Y, Lew AM. Cognate antigen engagement on parenchymal cells  stimulates CD8+ T cell proliferation in situ. Nat Commun. 2017 Apr 12;8:14809. doi: 10.1038/ncomms14809.PMID: 28401883 Free PMC article.
  10. Carrington EM, Zhan Y, Brady JL, Zhang JG, Sutherland RM, Anstee NS, Schenk RL, Vikstrom IB, Delconte RB, Segal D, Huntington ND, Bouillet P, Tarlinton DM, Huang DC, Strasser A, Cory S,  Herold MJ, Lew AM. Anti-apoptotic proteins BCL-2, MCL-1 and A1 summate collectively to maintain survival of immune cell populations both in vitro and in vivo. Cell Death Differ. 2017 May;24(5):878-888. doi: 10.1038/cdd.2017.30. Epub 2017 Mar 31.PMID: 28362427 Free PMC article.

 

Further publications