Andrew Lew-Publications

Andrew Lew-Publications

Selected publications

  1. Huang B, Chen Z, Geng L, Wang J, Liang H, Cao Y, Chen H, HuangW, Su M, Wang H, Xu Y, Liu Y, Lu B, Xian H, Li H, Li H, Ren L, Xie J, Ye L, Wang H, Zhao J, Zhang L, Zhang T, Xu B, Che D, Si W, Gu X, Zeng L, Wang Y, Li D, Zhan Y, Delfouneso D, Lew AM, Tang WH, Zhang Y, Gong S, Bai F, Yang M, Zhang Y. Mucosal profiling of pediatric-onset colitis and IBD reveals a common pathogenesis and therapeutic pathways. 2019. Cell In press
  2. Chopin M, Lun AT, Zhan Y, Schreuder J, Coughlan H, D'Amico A, Mielke LA, Almeida FF, Kueh AJ, Dickins RA, Belz GT, Naik SH, Lew AM, Bouillet P, Herold MJ, Smyth GK, Corcoran LM, Nutt SL (2019) Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT. Immunity. 2019 Jan 15;50(1):77-90.e5. PMID: 30611612
  3. Zhan Y, Wang N, Vasanthakumar A, Zhang Y, Chopin M, Nutt SL, Kallies A, Lew AM. CCR2 enhances CD25 expression by the Foxp3+ regulatory T cells and regulates their abundance independent of chemotaxis and CCR2+ myeloid cells. 2018. Cell Mol Immunol In press
  4. Sutherland RM, Londrigan SL, Brady JL, Carrington EM, Marchingo JM, Heinzel S, Hodgkin PD, Graham KL, Kay TW, Zhan Y, Lew AM. Cognate antigen engagement on parenchymal cells stimulates CD8 T cell proliferation in situ. Nat Commun. 2017 Apr 12;8:14809. PMID: 28401883
  5. Carrington EM, Zhan Y, Brady JL, Zhang JG, Sutherland RM, Anstee NS, Schenk RL, Vikstrom IB, Delconte RB, Segal D, Huntington ND, Bouillet P, Tarlinton DM, Huang DCS, Strasser A, Cory S, Herold MJ, Lew AM. Anti-apoptotic BCL-2 family proteins can summate as a quantitative collective to maintain survival of immune cell populations. Cell Death Differ. 2017 May;24(5):878-888. PMID: 28362427
  6. Zhan Y, Chow KV, Soo P, Xu Z, Brady JL, Lawlor KE, Masters SL, O'keeffe M, Shortman K, Zhang JG, Lew AM. Plasmacytoid dendritic cells are short-lived: reappraising the influence of migration, genetic factors and activation on estimation of lifespan. Sci Rep. 2016 Apr 26;6:25060. doi: 10.1038/srep25060. PMID: 27112985 
  7. Chow KV, Sutherland RM*, Zhan Y*, Lew AM*. Monocyte-Derived Dendritic Cells Promote Th Polarization, whereas Conventional Dendritic Cells Promote Th Proliferation. J Immunol. 2016 Jan 15;196(2):624-36. doi: 10.4049/jimmunol.1501202. Epub 2015 Dec 9. PMID: 26663720 
  8. Johanson TM, Keown AA, Cmero M, Yeo JH, Kumar A, Zhan Y*, Chong MM*, Lew AM*. Drosha controls dendritic cell development by cleaving messenger RNAs encoding inhibitors of myelopoiesis. Nat Immunol. 2015 Nov;16(11):1134-41. doi: 10.1038/ni.3293. Epub 2015 Oct 5. PMID: 26437240 
  9. Carrington EM, Zhang JG, Sutherland RM, Vikstrom IB, Brady JL, Soo P, Vremec D, Allison C, Lee EF, Fairlie WD, Bouillet P, Grabow S, Ottina E, Herold MJ, Pellegrini M, Huang DC, Tarlinton DM, Strasser A, Zhan Y*, Lew AM*. Prosurvival Bcl-2 family members reveal a distinct apoptotic identity between conventional and plasmacytoid dendritic cells. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4044-9. doi: 10.1073/pnas.1417620112. Epub 2015 Mar 16. PMID: 25775525 
  10. Marchingo JM, Kan A, Sutherland RM, Duffy KR, Wellard CJ, Belz GT, Lew AM, Dowling MR, Heinzel S, Hodgkin PD. Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion. Science. 2014 Nov 28;346(6213):1123-7. doi: 10.1126/science.1260044. PMID: 25430770 

 

* Co-senior authors

 

Further publications