Selected publications

1. Melanie Heinlein, Luke C Gandolfo, Kelin Zhao, Charis E Teh, Nghi Nguyen, Jonathan B Baell, Yael Goldfarb, Jakub Abramson, Johannes Wichmann , Anne K Voss, Andreas Strasser, Gordon K Smyth, Tim Thomas, Daniel H D Gray. The acetyltransferase KAT7 is required for thymic epithelial cell expansion, expression of AIRE target genes, and thymic tolerance. Sci Immunol. 2022 Jan 21;7(67):eabb6032. doi: 10.1126/sciimmunol.abb6032. Epub 2022 Jan 21. PMID: 35061506
2. Jain R., Zhao K., Sheridan J.M., Heinlein M., Kupresanin F., Abeysekera W., Hall C., Rickard J., Bouillet P., Walczak H., Strasser A., Silke J. and Gray D.H.D. Dual roles for LUBAC signaling in thymic epithelial cell development and survival. Cell Death and Differentiation, Aug 11 doi 10.1038/s41418-021-00850-8.
3. Teh, C.E.*, Robbins, A.K.*, Henstridge, D.C., Dewson, G., Diepstraten, S.T., Kelly, G., Febbraio, M.A., Gabriel, S.S., O'Reilly, L.A., Strasser, A., and Gray, D.H.D. (* co-first authors) MCL-1 is essential for survival but dispensable for metabolic fitness of FOXP3(+) regulatory T cells. Cell Death and Differentiation. 2020 Jul 1. doi: 10.1038/s41418-020-0585-1.
4. Teh, C.E., Gong, J.N., Segal, D., Tan, T., Vandenberg, C.J., Fedele, P.L., Low, M.S.Y., Grigoriadis, G., Harrison, S.J., Strasser, A., Roberts, A.W., Huang, D.C.S., Nolan, G.P.*,#, Gray, D.H.D.*,#, and Ko, M.E*. Deep profiling of apoptotic pathways with mass cytometry identifies a synergistic drug combination for killing myeloma cells. (* co-senior author; # corresponding authors) Cell Death and Differentiation. 2020 Jul;27(7):2217-2233. doi: 10.1038/s41418-020-0498-z.
5. Agarwal, R., Y.-C. Chan, C.S. Tam, T. Hunter, D. Vassiliadis, C.E. Teh, R. Thijssen, P. Yeh, S.Q. Wong, S. Ftouni, E.Y.N. Lam, M.A. Anderson, C. Pott, O. Gilan, C.C. Bell, K. Knezevic, P. Blombery, K. Rayeroux, A. Zordan, J. Li, D.C.S. Huang, M. Wall, J.F. Seymour, D.H.D. Gray, A.W. Roberts, M.A. Dawson, and S.-J. Dawson. Dynamic molecular monitoring reveals that SWI-SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma. Nature Medicine Jan 2019; 25(1): 119-129. doi: 10.1038/s41591-018-0243-z.
6. Jain, R., Sheridan, J.M., Policheni, A., Heinlein, M., Gandolfo, L.C., Dewson, G., Smyth, G.K., Sansom, S.N., Fu, N.Y., Visvader, J.E., Hollander, G.A., Strasser, A., and Gray, D.H.D.  A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice. Blood 2017, Dec 7;130(23):2504-2515. Doi: 10.1182/blood-2017-03-771576. 
7. Teh, C.E., Lalaoui, N., Jain, R., Policheni, A.N., Heinlein, M., Alvarez-Diaz, S., Sheridan, J.M., Rieser, E., Deuser, S., Darding, M., Koay, H.-F., Hu, Y., Kupresanin, F., O'Reilly, L.A., Godfrey, D.I., Smyth, G.K., Bouillet, P., Strasser, A., Walczak, H., Silke, J., and Gray, D.H.D. Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis. Nature Communications 2016; 7: 13353. Doi: 10.1038/ncomms13353.
8. Liston, A., and Gray, D.H.D. Homeostatic control of regulatory T cell diversity. Nature Reviews Immunology 2014; 14(3): 154-65. ISI Web of Science Highly Cited Paper
9. Pierson, W., Cauwe, B., Policheni, A., Schlenner, S.M., Franckaert, D., Berges, J., Humblet-Baron, S., Schonefeldt, S., Herold, M.J., Hildeman, D., Strasser, A., Bouillet, P., Lu, L.-F., Matthys, P., Freitas, A.A., Luther, R.J., Weaver, C.T., Dooley, J., Gray, D.H.D.*, and Liston, A.* (joint senior/corresponding authors) Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3(+) regulatory T cells. Nature Immunology 2013; 14(9): 959-65.
10. Gray, D.H.D., Kupresanin, F., Berzins, S.P., Herold, M.J., O'Reilly, L.A., Bouillet, P., and Strasser, A. The BH3-Only Proteins Bim and Puma Cooperate to Impose Deletional Tolerance of Organ-Specific Antigens. Immunity 2012; 37(3): 451-62.