Grant Dewson-Projects

Grant Dewson-Projects


Controlling apoptotic cell death in cancer

Apoptotic cell death is critical in development but is also emerging as an important therapeutic target to treat diseases ranging from cancer to neurodegenerative conditions. 

My lab utilises novel cell biology and biochemical approaches to interrogate how apoptosis is controlled so that we might better target the process to treat disease. We have identified several novel putative regulators of apoptosis. 

This project will characterise the role of these proteins in regulating cell death and also investigate their potential role in cancer development. The project will involve diverse approaches including cell culture, mutagenesis, protein chemistry, mass spectrometry and high-resolution microscopy.