Joanna Groom-Lab team

Joanna Groom-Lab team

Researcher: 
We work closely with the other members of the Immunology division and the Institute's Centre for Dynamic Imaging.
We seek driven students and scientists who are open to new technologies and interested in dissecting the influence of cell migration on immune outcomes.

Team

Amania Sheikh, PhD Student submitted, BAppSci, BMedBiotech(Masters) Pakistan
Key publication: Sheikh AA, Cooper L, Feng M, Souza-Fonseca-Guimaraes F, Lafouresse F, Duckworth BC, Huntington ND, Moon JJ, Pellegrini M, Nutt SL, Belz GT, Good-Jacobson KL, Groom JR. Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection.  Cell Rep. 2019 Aug 13;28(7):1758-1772. PMID: 31412245

Lennard Dalit, PhD Student, BSci USA BSci Immunology(Hons) Qld
Key publication: Kealy L, Di Pietro A, Hailes L, Scheer S, Dalit L, Groom JR, Zaph C, Good-Jacobson KL. The Histone Methyltransferase DOT1L Is Essential for Humoral Immune Responses. Cell Rep 2020 Dec 15;33(11):108504. PMID: 33326791

Brigette Duckworth, PhD Student, BMedSci BSc(Hons) Melbourne
Key publication: Duckworth DC, Lafouresse F, Wimmer VC, Broomfield BJ, Alexandre YO, Sheikh AA, Qin RZ, Alvarado C, Mielke LA, Pellegrini M, Mueller SN, Boudier T, Rogers KL, Groom JR. Effector and stem-like memory cell fates are imprinted in distinct lymph node niches directed by CXCR3 ligands. Nat Immunol 2021 Apr;22(4):434-448. PMID: 33649580

Raymond Qin, Honours Student, BMedSci BSc(Hons) Melbourne
Key publication: Ly A, Liao Y, Pietrzak H, Ioannidis LJ, Sidwell T, Gloury R, Doerflinger M, Triglia T, Qin RZ, Groom JR, Belz GT, Good-Jacobson KL, Shi W, Kallies A, Hansen DS. Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria. Cell Rep. 2019 Nov 19;29(8):2257-2269. PMID: 31747599

Carolina Alvarado, Research Assistant, BVSc Peru MAppSci (Masters) Sydney Animal Technology Cert Melbourne
Key publication: Duckworth DC, Lafouresse F, Wimmer VC, Broomfield BJ, Alexandre YO, Sheikh AA, Qin RZ, Alvarado C, Mielke LA, Pellegrini M, Mueller SN, Boudier T, Rogers KL, Groom JR. Effector and stem-like memory cell fates are imprinted in distinct lymph node niches directed by CXCR3 ligands. Nat Immunol 2021 Apr;22(4):434-448. PMID: 33649580

Ben Broomfield, Research Assistant, BMedSci BSc(Hons) Melbourne
Key publication: Duckworth DC, Lafouresse F, Wimmer VC, Broomfield BJ, Alexandre YO, Sheikh AA, Qin RZ, Alvarado C, Mielke LA, Pellegrini M, Mueller SN, Boudier T, Rogers KL, Groom JR. Effector and stem-like memory cell fates are imprinted in distinct lymph node niches directed by CXCR3 ligands. Nat Immunol 2021 Apr;22(4):434-448. PMID: 33649580

Super Content: 

Our researchers have identified a molecular switch that impacts immune responses to viral infections, and whether or not protective antibodies are produced.

Two scientists with imaging equipment

A new imaging technique is shining a light on immune responses and setting the scene for enhancing immune memory to optimise vaccine strategies.