Selected publications

1. Linossi E, Li K, Veggiani G, Tan C, Dehkhoda F, Hockings C, Calleja D, Keating N, Feltham R, Brooks A, Li S, Sidhu S, Babon JJ, Kershaw NJ^†, Nicholson SE^† A novel exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands, Nat Commun, 2021, PMID: 34857742
2. Morris R, Zhang YY, Ellyard J, Vinuesa C, Murphy JJ, Laktyushin A, Kershaw NJ†, Babon JJ^† Structural and functional analysis of target recognition by the lymphocyte adaptor protein LNK, Nat Commun, 2021, PMID: PMID: 34671038
3. Liau NPD, Laktyushin A, Lucet IS, Murphy JM, Yao S, Whitlock E, Callaghan K, Nicola NA, Kershaw NJ^†, Babon JJ^† The molecular basis of JAK/STAT inhibition by SOCS1, Nat Commun, 2018 PMID: 29674694
4. Kershaw NJ, Church NL, Griffin MD, Luo CS, Adams TE, Burgess AW, Notch ligand delta-like1: X-ray crystal structure and binding affinity. Biochem J., 2015 PMID: 25715738
5. Kershaw NJ, Murphy JM, Liau NP, Varghese LN, Laktyushin A, Whitlock EL, Lucet IS, Nicola NA, Babon JJ. SOCS3 binds specific receptor-JAK complexes to control cytokine signaling by direct kinase inhibition.
   Nat Struct Mol Biol., 2013, PMID: 23454976

    

Reviews

1. Morris, R, Kershaw NJ, Babon JJ, The molecular details of cytokine signaling via the JAK/STAT pathway, Protein Sci, 2018, PMID: 30267440
2. Kershaw NJ, Murphy JM, Lucet IS, Nicola NA, Babon JJ., Regulation of Janus kinases by SOCS proteins., Biochem Soc Tran, 2013, PMID: 23863176

^† Joint corresponding author

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