Luk IY, Mooi JK, Mouradov D, Tan T, Scott CM, Chionh F, Jenkins LJ, Reehorst CM, Nightingale R, Savas P, Tse JW, Crake RL, Batlle E, Arango D, Dopeso H, Gibbs P, Tebbutt NC, Luwor RB, Scott AM, Basheer F, Dhillon AS, Clemons NJ, Williams DS, Firestein R, Sieber OM, Mariadason JM. Model systems and unique biological features of high and low-grade colorectal cancer (CRC) revealed by xenografting 84 human CRC cell lines. Communications Biology. 2025;8(1):10.1038/s42003-025-08251-0
Xi X, Liu L, Tuano N, Tailhades J, Mouradov D, Steen J, Sieber O, Cryle M, Nguyen-Dumont T, Segelov E, Rosenbluh J. SRP19 and the protein secretion machinery is a targetable vulnerability in cancers with APC loss. Proceedings of the National Academy of Sciences of the United States of America. 2025;122(15):10.1073/pnas.2409677122
Millward J, He Z, Nibali A, Mouradov D, Mielke LA, Tran K, Chou A, Hawkins NJ, Ward RL, Gill AJ, Sieber OM, Williams DS. Automated deep learning-based assessment of tumour-infiltrating lymphocyte density determines prognosis in colorectal cancer. Journal of Translational Medicine. 2025;23(1):10.1186/s12967-025-06254-3
Al-Ani A, Pang J, Patel K, Young SN, Kong I, Chen JJ, Barrios M, Rickard J, Chen S, Foroughi S, Cawthorne W, Jacobsen A, Jois A, Weir A, Whitehead L, Rajasekhar P, Horne C, Azeez I, Zhang Y, Sieber O, Spelman T, Giulino-Roth L, Hawkins E, Rogers K, Bowden R, Nicholson S, Lawlor K, Samson AL, Vince JE, Murphy JM, Christensen B. DOP109 A necroptotic-to-apoptotic signaling axis underlies inflammatory bowel disease. Journal of Crohn’s and Colitis. 2025;19(Supplement_1):10.1093/ecco-jcc/jjae190.0148
Storey C, Gately L, Drummond K, Gogos A, Mouradov D, Christie M, Brasier H, Priest E, Fakhri A, Gibbs P, Sieber O. TMOD-15. TOWARD BRAIN CANCER ORGANOID-INFORMED PRECISION MEDICINE FOR GLIOBLASTOMA. Neuro-Oncology. 2024;26(Supplement_8):10.1093/neuonc/noae165.1279
Brydon SC, Poad BLJ, Fang M, Rustam YH, Young RSE, Mouradov D, Sieber OM, Mitchell TW, Reid GE, Blanksby SJ, Marshall DL. Cross-Validation of Lipid Structure Assignment Using Orthogonal Ion Activation Modalities on the Same Mass Spectrometer. Journal of The American Society for Mass Spectrometry. 2024;35(8):10.1021/jasms.4c00221
Tan T, Mouradov D, Gibbs P, Sieber OM. Protocol for generation of and high-throughput drug testing with patient-derived colorectal cancer organoids. STAR Protocols. 2024;5(2):10.1016/j.xpro.2024.103090
Jenkins LJ, Luk IY, Chionh F, Tan T, Needham K, Ayton J, Reehorst CM, Vukelic N, Sieber OM, Mouradov D, Gibbs P, Williams DS, Tebbutt NC, Desai J, Hollande F, Dhillon AS, Lee EF, Merino D, Fairlie WD, Mariadason JM. BCL-XL inhibitors enhance the apoptotic efficacy of BRAF inhibitors in BRAFV600E colorectal cancer. Cell Death & Disease. 2024;15(3):10.1038/s41419-024-06478-z
Wang Z, Burigotto M, Ghetti S, Vaillant F, Tan T, Capaldo BD, Palmieri M, Hirokawa Y, Tai L, Simpson DS, Chang C, Huang AS, Lieschke E, Diepstraten ST, Kaloni D, Riffkin C, Huang DCS, Suen CSNLW, Garnham AL, Gibbs P, Visvader JE, Sieber OM, Herold MJ, Fava LL, Kelly GL, Strasser A. Loss-of-Function but Not Gain-of-Function Properties of Mutant TP53 Are Critical for the Proliferation, Survival, and Metastasis of a Broad Range of Cancer Cells. Cancer Discovery. 2024;14(2):10.1158/2159-8290.cd-23-0402
Tan T, Mouradov D, Lee M, Gard G, Hirokawa Y, Li S, Lin C, Li F, Luo H, Wu K, Palmieri M, Leong E, Clarke J, Sakthianandeswaren A, Brasier H, Tie J, Tebbutt NC, Jalali A, Wong R, Burgess AW, Gibbs P, Sieber OM. Unified framework for patient-derived, tumor-organoid-based predictive testing of standard-of-care therapies in metastatic colorectal cancer. Cell Reports Medicine. 2023;4(12):10.1016/j.xcrm.2023.101335
