Selected publications

1. Marchingo JM, Kan A, Sutherland RM, Duffy KR, Wellard CJ, Belz GT, Lew AM, Dowling MR, Heinzel S, Hodgkin PD. T cell signaling. Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion. Science 346: 1123-1127 PMID: 25430770.
2. Dowling MR, Kan A, Heinzel S, Zhou JH, Marchingo JM, Wellard CJ, Markham JF, Hodgkin PD. Stretched cell cycle model for proliferating lymphocytes. Proc Natl Acad Sci U S A. 2014 Apr 29;111(17):6377-82. PMID: 24733943.
3. Hawkins ED, Turner ML, Wellard CJ, Zhou JH, Dowling MR, Hodgkin PD. Quantal and graded stimulation of B lymphocytes as alternative strategies for regulating adaptive immune responses. Nat Commun. 2013;4:2406. PMID: 24009041.
4. Duffy KR, Wellard CJ, Markham JF, Zhou JH, Holmberg R, Hawkins ED, Hasbold J, Dowling MR, Hodgkin PD. Activation-induced B cell fates are selected by intracellular stochastic competition. Science. 2012 Jan 20;335(6066):338-41. PMID: 22223740.
5. Duffy KR, Hodgkin PD. Intracellular competition for fates in the immune system. Trends Cell Biol. 2012 Sep;22(9):457-64. PMID: 22727035.
6. Hawkins ED, Markham JF, McGuinness LP, Hodgkin PD. A single-cell pedigree analysis of alternative stochastic lymphocyte fates. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13457-62. PMID: 19633185.
7. Hawkins ED, Turner ML, Dowling MR, van Gend C, Hodgkin PD. A model of immune regulation as a consequence of randomized lymphocyte division and death times. Proc Natl Acad Sci U S A. 2007 Mar 20;104(12):5032-7. PMID: 17360353.
8. Kallies A, Hasbold J, Tarlinton DM, Dietrich W, Corcoran LM, Hodgkin PD, Nutt SL. Plasma cell ontogeny defined by quantitative changes in blimp-1 expression. J Exp Med. 2004 Oct 18;200(8):967-77. PMID: 15492122.
9. Hasbold J, Corcoran LM, Tarlinton DM, Tangye SG, Hodgkin PD. Evidence from the generation of immunoglobulin G-secreting cells that stochastic mechanisms regulate lymphocyte differentiation. Nat Immunol. 2004 Jan;5(1):55-63. PMID: 14647274.
10. Gett AV, Hodgkin PD. A cellular calculus for signal integration by T cells. Nat Immunol. 2000 Sep;1(3):239-44. PMID: 10973282.

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