Professor Robert Brink - Garvan Institute of Medical Research

Professor Robert Brink - Garvan Institute of Medical Research

Location: 
Davis Auditorium
Start Time: 
Thu, 17/10/2019 - 1:00pm
End Time: 
Thu, 17/10/2019 - 2:00pm

​Class and position - positive and negative discrimination in the germinal centre

​Special seminar hosted by Dr Vanessa Bryant

Prof Robert Brink obtained his PhD in 1992 from the University of Sydney (Centenary Institute), studying the mechanisms that prevent autoantibody production by self-reactive B cells. He worked at the Whitehead Institute in Boston from 1994-96 before returning to the Centenary Institute where he developed a series of genetically modified mouse models to investigate antibody responses and lymphocyte development. In 2006 Prof Brink was recruited to the Garvan Institute in Sydney to head the B Cell Biology group. He served as Head of the Institute’s Immunology Division from 2010-14 and established the MEGA facility for production of GM mice using CRISPR/Cas9 technology. His major research focus continues to be the regulation of B cell survival and antibody production during immune and autoimmune responses with particular interest in the regulation and function of the germinal centre reaction.